Respiratory management

Lyzal M

Montelukast+Levocetirizine a combined therapy is prescribed for the systemic treatment of allergic reactions such as chronic urticaria, obstructive airway diseases and rhinitis.

Lyzal M Tablets is a combination of Montelukast Sodium & Levocetirizine Dihydrochloride. Montelukast sodium is an orally active compound that binds with high affinity and selectivity to the CysLT1 receptor. Montelukast inhibits physiologic actions of LTD 4 at the CysLT1 receptor without any agonist activity.
It therefore acts as a leukotriene receptor antagonist Levocetirizine, the R-enantiomer of cetirizine, is a potent and selective antagonist of peripheral H1-receptors. It has been demonstrated by recent studies that the treatment of AR with concomitant administration of an antileukotriene (montelukast) and an antihistamine (levocetirizine), shows significantly better symptom relief compared with the modest improvement of rhinitis symptomatology with each of the treatments alone.

Broad spectrum anti histaminic and leukotriene receptor antagonist

The most Reliable and Affordable Anti-allergic & effective leukotriene inhibitor combination

Highly potent 3rd generation H – Receptor antagonist

Reduces broncho-constriction caused by the leukotriene

Least sedation with no CNS side effect

Complete Anti-allergy for early and late phase of allergy

Relieves runny nose redness, sneezing, itching & tearing of eye caused by hay fever & Rhinitis

Treat symptoms of hives, itching and Rash

Acute Allergic reaction due to food, Drug & Insect bite

Product Info

  • Uses
  • Side Effects
  • Precautions
  • Interactions
  • Used in

Montelukast+Levocetirizine a combined therapy is prescribed for the systemic treatment of allergic reactions such as chronic urticaria, obstructive airway diseases and rhinitis.

Dyspepsia, abdominal pain, rash, dizziness, headache, fatigue, and somnolence. Sometimes, hypersensitivity, irritability, restlessness, insomnia, vomiting and diarrhoea may occur. In rare cases, patients may present with systemic eosinophilia, sometimes presenting with clinical features of Churg-Strauss Syndrome.

Montelukast + Levocetirizine is contraindicated in patients with an allergy to either or both drugs, hepatic impairment, NSAID allergy, Churg-Strauss syndrome. Montelukast + Levocetirizine is contraindicated in children less than six months of age.

Montelukast + Levocetirizine can cause dizziness. Do not drive vehicles or operate heavy machineries that need alertness.

Montelukast + Levocetirizine may interact with phenytoin, CNS depressants, rifampicin, prednisone and phenobarbital.

• Seasonal Allergic Rhinitis

• Perennial Allergic Rhinitis

• Atopic Dermatitis

• Asthma / Ocular Allergies

• Urticaria & Urticarial Lesians

• Chronic Idiopathic Urticaria

• Atopic Eczema & contact dermatitis

• Extrinsic asthma